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miR-495 and miR-5688 are down-regulated in non-small cell lung cancer under hypoxia to maintain interleukin-11 expression

miR-495 and miR-5688 are down-regulated in non-small cell lung cancer under hypoxia to maintain interleukin-11 expression
Posted by Rachael

Background: Hypoxia is a hallmark of cancer and is associated with poor prognosis. However, the molecular mechanism by which hypoxia promotes tumor development is still unclear. MicroRNAs dysregulation has been shown to play an important role in the tumor and the tumor micro. Here, we investigated the role of miR-495 and miR-5688 in lung cancer of human non-small cell (NSCLC) and their underlying mechanisms.


Methods: The expression level of miR-495 and miR-5688 in human NSCLC tissue specimens was measured by quantitative real-time polymerase chain reaction (qRT-PCR). Deferoxamine (DFO) is used to determine whether the regulation of miR-495 and miR-5688 under hypoxia depends on the hypoxia-inducible factor 1-alpha (HIF-1α).

Furthermore, the function of miR-495 and miR-5688 in tumor progression was evaluated using colony formation, 3- (4,5-dimethylthiazol-2-yl) -5- (3-carboxymethoxyphenyl) -2- (4-sulfophenyl) -2H -tetrazolium (MTS), wound healing, transwell test, and the xenograft model. Two algorithms, PicTAR and Targetscan, used to predict the two miRNAs target gene is, and dual-luciferase reporter assay was performed to confirm the target. Tests are two-tailed paired t, Pearson correlation analysis and Fisher probability test conducted for statistical analysis.


Results: The two miRNAs, miR-495 and miR-5688, was found to participate in the development of NSCLC under hypoxia. They were down-regulated in NSCLC tissue compared to normal tissue. We determined that hypoxia causes down-regulation of miR-495 and miR-5688 in NSCLC cells, independent of HIF-1α and energy metabolism of cells. In addition, miR-495 and miR-5688 suppressed cell proliferation, migration and invasion in vitro

miR-495 and miR-5688 are down-regulated in non-small cell lung cancer under hypoxia to maintain interleukin-11 expression
miR-495 and miR-5688 are down-regulated in non-small cell lung cancer under hypoxia to maintain interleukin-11 expression

. The NSCLC xenograft models indicate that miR-495 and miR-5688 inhibits tumor formation in vivo. Interestingly, we found that miR-495 and miR-5688 have the same target, interleukin-11 (IL-11). Human recombinant IL-11 is counteracted the effects of miR-495 and miR-5688 in NSCLC cells, suggesting that miR-495 and miR-5688 held their tumor suppressor role by pressing IL-11 expression.

Conclusion: We found hypoxia down-regulated the expression level of miR-495 and miR-5688 in NSCLC to increase IL-11 expression and tumor progression, suggesting that miR-495 / miR-5688 / IL-11 axis can serve as a therapeutic target and a potential biomarker for NSCLC.

Variants in IL 6ST selectively IL – 11 signal defects in the Human and mouse Gp130 cytokine receptor subunit encoded by the IL 6ST is a cytokine receptors together for ten of IL -6 family. We describe non-identical homozygous variant in IL 6ST (p.R281Q) in patients with craniosynostosis and maintain primary teeth. We characterize the effects of variants in cytokine signaling in vitro using cell lines and cells transfected patient-derived primary and support these findings using mice models with appropriate genome -edited variant Il6st that p.R279Q.

Rat Interleukin 17B (IL17B) ELISA Kit

DLR-IL17B-Ra-48T 48T
EUR 475
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 17B (IL17B) in samples from serum, plasma or other biological fluids.

Rat Interleukin 17B (IL17B) ELISA Kit

DLR-IL17B-Ra-96T 96T
EUR 616
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 17B (IL17B) in samples from serum, plasma or other biological fluids.

Human Interleukin 17B (IL17B) ELISA Kit

RDR-IL17B-Hu-48Tests 48 Tests
EUR 458

Human Interleukin 17B (IL17B) ELISA Kit

RDR-IL17B-Hu-96Tests 96 Tests
EUR 633

Mouse Interleukin 17B (IL17B) ELISA Kit

RDR-IL17B-Mu-48Tests 48 Tests
EUR 470

Mouse Interleukin 17B (IL17B) ELISA Kit

RDR-IL17B-Mu-96Tests 96 Tests
EUR 651

Rat Interleukin 17B (IL17B) ELISA Kit

RDR-IL17B-Ra-48Tests 48 Tests
EUR 495

Rat Interleukin 17B (IL17B) ELISA Kit

RDR-IL17B-Ra-96Tests 96 Tests
EUR 685

Human Interleukin 17B (IL17B) ELISA Kit

RD-IL17B-Hu-48Tests 48 Tests
EUR 439

Human Interleukin 17B (IL17B) ELISA Kit

RD-IL17B-Hu-96Tests 96 Tests
EUR 606

Mouse Interleukin 17B (IL17B) ELISA Kit

RD-IL17B-Mu-48Tests 48 Tests
EUR 450

Mouse Interleukin 17B (IL17B) ELISA Kit

RD-IL17B-Mu-96Tests 96 Tests
EUR 622

Rat Interleukin 17B (IL17B) ELISA Kit

RD-IL17B-Ra-48Tests 48 Tests
EUR 473

Rat Interleukin 17B (IL17B) ELISA Kit

RD-IL17B-Ra-96Tests 96 Tests
EUR 655

Recombinant Interleukin 17B (IL17B)

4-RPB700Hu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 17B expressed in: E.coli

Recombinant Interleukin 17B (IL17B)

4-RPB700Ra01
  • EUR 508.58
  • EUR 239.00
  • EUR 1632.16
  • EUR 610.72
  • EUR 1121.44
  • EUR 403.00
  • EUR 3930.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Interleukin 17B expressed in: E.coli

Interleukin 17B (IL17B) Antibody

20-abx101512
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 17B (IL17B) Antibody

20-abx101513
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 17B (IL17B) Antibody

abx038115-100ug 100 ug
EUR 391

Interleukin 17B (IL17B) Antibody

20-abx216191
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Interleukin 17B (IL17B) Antibody

abx234226-100ug 100 ug
EUR 551

Interleukin 17B (IL17B) Antibody

20-abx177117
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug

Interleukin 17B (IL17B) Antibody

20-abx177118
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug

Interleukin 17B (IL17B) Antibody

20-abx173104
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug

Interleukin 17B (IL17B) Antibody

20-abx173105
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug

Interleukin 17B (IL17B) Antibody

20-abx330118
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Rat Interleukin 17B (IL17B) Protein

20-abx067473
  • EUR 704.00
  • EUR 286.00
  • EUR 2193.00
  • EUR 843.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Interleukin 17B (IL17B) Protein

20-abx067475
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Interleukin 17B (IL17B) Protein

20-abx653985
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Interleukin 17B (IL17B) Protein

20-abx653986
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Interleukin- 17B, IL17B ELISA KIT

ELI-06753h 96 Tests
EUR 824

Mouse Interleukin- 17B, Il17b ELISA KIT

ELI-06754m 96 Tests
EUR 865

Human Interleukin 17B (IL17B)CLIA Kit

SCB700Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Human Interleukin 17B (IL17B)CLIA Kit

SCB700Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Human Interleukin 17B (IL17B)CLIA Kit

SCB700Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Human Interleukin 17B (IL17B)CLIA Kit

SCB700Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Human Interleukin 17B (IL17B) CLIA Kit

4-SCB700Hu
  • EUR 5698.00
  • EUR 3061.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Interleukin 17B (IL17B)Serum, plasma and other biological fluids

Mouse Interleukin 17B (IL17B)CLIA Kit

SCB700Mu-10x96wellstestplate 10x96-wells test plate
EUR 5804.88
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Mouse Interleukin 17B (IL17B)CLIA Kit

SCB700Mu-1x48wellstestplate 1x48-wells test plate
EUR 565.7
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Mouse Interleukin 17B (IL17B)CLIA Kit

SCB700Mu-1x96wellstestplate 1x96-wells test plate
EUR 765.28
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Mouse Interleukin 17B (IL17B)CLIA Kit

SCB700Mu-5x96wellstestplate 5x96-wells test plate
EUR 3143.76
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Mouse Interleukin 17B (IL17B) CLIA Kit

4-SCB700Mu
  • EUR 5855.00
  • EUR 3144.00
  • EUR 766.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Mouse Interleukin 17B (IL17B)Serum, plasma and other biological fluids

Rat Interleukin 17B (IL17B)CLIA Kit

SCB700Ra-10x96wellstestplate 10x96-wells test plate
EUR 6119.04
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Rat Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Rat Interleukin 17B (IL17B)CLIA Kit

SCB700Ra-1x48wellstestplate 1x48-wells test plate
EUR 591.57
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Rat Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Rat Interleukin 17B (IL17B)CLIA Kit

SCB700Ra-1x96wellstestplate 1x96-wells test plate
EUR 802.24
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Rat Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Rat Interleukin 17B (IL17B)CLIA Kit

SCB700Ra-5x96wellstestplate 5x96-wells test plate
EUR 3310.08
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Rat Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Rat Interleukin 17B (IL17B) CLIA Kit

4-SCB700Ra
  • EUR 6170.00
  • EUR 3311.00
  • EUR 803.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Rat Interleukin 17B (IL17B)Serum, plasma and other biological fluids

Human Interleukin 17B (IL17B) ELISA Kit

SEB700Hu-10x96wellstestplate 10x96-wells test plate
EUR 4502.43
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Human Interleukin 17B (IL17B) ELISA Kit

SEB700Hu-1x48wellstestplate 1x48-wells test plate
EUR 458.44
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Human Interleukin 17B (IL17B) ELISA Kit

SEB700Hu-1x96wellstestplate 1x96-wells test plate
EUR 612.05
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Human Interleukin 17B (IL17B) ELISA Kit

SEB700Hu-5x96wellstestplate 5x96-wells test plate
EUR 2454.23
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Human Interleukin 17B (IL17B) ELISA Kit

4-SEB700Hu
  • EUR 4553.00
  • EUR 2405.00
  • EUR 613.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Interleukin 17B (IL17B) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.

Mouse Interleukin 17B (IL17B) ELISA Kit

SEB700Mu-10x96wellstestplate 10x96-wells test plate
EUR 4626.78
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Mouse Interleukin 17B (IL17B) ELISA Kit

SEB700Mu-1x48wellstestplate 1x48-wells test plate
EUR 468.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Mouse Interleukin 17B (IL17B) ELISA Kit

SEB700Mu-1x96wellstestplate 1x96-wells test plate
EUR 626.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Mouse Interleukin 17B (IL17B) ELISA Kit

SEB700Mu-5x96wellstestplate 5x96-wells test plate
EUR 2520.06
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Mouse Interleukin 17B (IL17B) ELISA Kit

4-SEB700Mu
  • EUR 4677.00
  • EUR 2471.00
  • EUR 627.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Interleukin 17B (IL17B) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.

Rat Interleukin 17B (IL17B) ELISA Kit

SEB700Ra-10x96wellstestplate 10x96-wells test plate
EUR 4875.49
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Rat Interleukin 17B (IL17B) ELISA Kit

SEB700Ra-1x48wellstestplate 1x48-wells test plate
EUR 489.16
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Rat Interleukin 17B (IL17B) ELISA Kit

SEB700Ra-1x96wellstestplate 1x96-wells test plate
EUR 655.94
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Rat Interleukin 17B (IL17B) ELISA Kit

SEB700Ra-5x96wellstestplate 5x96-wells test plate
EUR 2651.73
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Interleukin 17B (IL17B) in serum, plasma and other biological fluids.

Rat Interleukin 17B (IL17B) ELISA Kit

4-SEB700Ra
  • EUR 4926.00
  • EUR 2602.00
  • EUR 656.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Interleukin 17B (IL17B) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.

Interleukin 17B (IL17B) Polyclonal Antibody (Human)

4-PAB700Hu01
  • EUR 239.00
  • EUR 2391.00
  • EUR 598.00
  • EUR 299.00
  • EUR 211.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 17B (IL17B)

Interleukin 17B (IL17B) Polyclonal Antibody (Rat)

4-PAB700Ra01
  • EUR 251.00
  • EUR 2589.00
  • EUR 643.00
  • EUR 317.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 17B (IL17B)

Mouse Interleukin-17B(IL17B) ELISA kit

CSB-EL011598MO-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin-17B (IL17B) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Interleukin-17B(IL17B) ELISA kit

1-CSB-EL011598MO
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin-17B(IL17B) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Interleukin 17B (IL17B) ELISA Kit

20-abx154238
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Interleukin 17B (IL17B) ELISA Kit

abx574703-96tests 96 tests
EUR 668

Mouse Interleukin 17B (IL17B) ELISA Kit

abx574963-96tests 96 tests
EUR 668

Human IL17B/ Interleukin-17B ELISA Kit

E1264Hu 1 Kit
EUR 571

Mouse Il17b/ Interleukin-17B ELISA Kit

E0754Mo 1 Kit
EUR 546

Human Interleukin 17B (IL17B) CLIA Kit

20-abx190244
  • EUR 7911.00
  • EUR 4215.00
  • EUR 973.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Interleukin 17B (IL17B) CLIA Kit

20-abx190529
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Interleukin 17B (IL17B) CLIA Kit

20-abx190699
  • EUR 8443.00
  • EUR 4497.00
  • EUR 1036.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Interleukin 17B (IL17B) ELISA Kit

20-abx155721
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Interleukin 17B (IL17B) ELISA Kit

20-abx152021
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Interleukin 17B ELISA Kit (IL17B)

RK03755 96 Tests
EUR 521

Mouse Interleukin 17B ELISA Kit (IL17B)

RK02934 96 Tests
EUR 521

Human IL17B(Interleukin-17B) ELISA Kit

EH2104 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Interleukin 17B (IL17B) Polyclonal Antibody (Human), HRP

4-PAB700Hu01-HRP
  • EUR 305.00
  • EUR 2714.00
  • EUR 772.00
  • EUR 383.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 17B (IL17B). This antibody is labeled with HRP.

Interleukin 17B (IL17B) Polyclonal Antibody (Human), PE

4-PAB700Hu01-PE
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 17B (IL17B). This antibody is labeled with PE.

Interleukin 17B (IL17B) Polyclonal Antibody (Rat), APC

4-PAB700Ra01-APC
  • EUR 352.00
  • EUR 3383.00
  • EUR 939.00
  • EUR 450.00
  • EUR 223.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 17B (IL17B). This antibody is labeled with APC.

Interleukin 17B (IL17B) Polyclonal Antibody (Rat), Cy3

4-PAB700Ra01-Cy3
  • EUR 428.00
  • EUR 4469.00
  • EUR 1211.00
  • EUR 559.00
  • EUR 255.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 17B (IL17B). This antibody is labeled with Cy3.

Interleukin 17B (IL17B) Polyclonal Antibody (Rat), HRP

4-PAB700Ra01-HRP
  • EUR 322.00
  • EUR 2948.00
  • EUR 830.00
  • EUR 407.00
  • EUR 210.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 17B (IL17B). This antibody is labeled with HRP.

Interleukin 17B (IL17B) Polyclonal Antibody (Rat), PE

4-PAB700Ra01-PE
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 17B (IL17B). This antibody is labeled with PE.

Interleukin 17B (IL17B) Polyclonal Antibody (Human), APC

4-PAB700Hu01-APC
  • EUR 333.00
  • EUR 3113.00
  • EUR 872.00
  • EUR 423.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 17B (IL17B). This antibody is labeled with APC.

Interleukin 17B (IL17B) Polyclonal Antibody (Human), Biotinylated

4-PAB700Hu01-Biotin
  • EUR 303.00
  • EUR 2341.00
  • EUR 697.00
  • EUR 369.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 17B (IL17B). This antibody is labeled with Biotin.

Interleukin 17B (IL17B) Polyclonal Antibody (Human), Cy3

4-PAB700Hu01-Cy3
  • EUR 403.00
  • EUR 4109.00
  • EUR 1121.00
  • EUR 523.00
  • EUR 245.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 17B (IL17B). This antibody is labeled with Cy3.

Interleukin 17B (IL17B) Polyclonal Antibody (Human), FITC

4-PAB700Hu01-FITC
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 17B (IL17B). This antibody is labeled with FITC.

Interleukin 17B (IL17B) Polyclonal Antibody (Rat), Biotinylated

4-PAB700Ra01-Biotin
  • EUR 316.00
  • EUR 2539.00
  • EUR 747.00
  • EUR 388.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 17B (IL17B). This antibody is labeled with Biotin.

Interleukin 17B (IL17B) Polyclonal Antibody (Rat), FITC

4-PAB700Ra01-FITC
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 17B (IL17B). This antibody is labeled with FITC.

ELISA kit for Human IL17B (Interleukin 17B)

ELK2702 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Interleukin 17B from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Rat IL17B (Interleukin 17B)

ELK5674 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Interleukin 17B from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse IL17B (Interleukin 17B)

ELK4007 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Interleukin 17B from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Interleukin 17B (IL17B) Polyclonal Antibody (Rat), APC-Cy7

4-PAB700Ra01-APC-Cy7
  • EUR 585.00
  • EUR 6646.00
  • EUR 1759.00
  • EUR 781.00
  • EUR 326.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 17B (IL17B). This antibody is labeled with APC-Cy7.

Interleukin 17B (IL17B) Polyclonal Antibody (Human), APC-Cy7

4-PAB700Hu01-APC-Cy7
  • EUR 547.00
  • EUR 6106.00
  • EUR 1624.00
  • EUR 727.00
  • EUR 310.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 17B (IL17B). This antibody is labeled with APC-Cy7.

Mini Samples Mouse Interleukin 17B (IL17B) ELISA Kit

MEB700Mu-10x96wellstestplate 10x96-wells test plate
EUR 5523.45
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mini Samples Mouse Interleukin 17B (IL17B).

Mini Samples Mouse Interleukin 17B (IL17B) ELISA Kit

MEB700Mu-1x48wellstestplate 1x48-wells test plate
EUR 542.52
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mini Samples Mouse Interleukin 17B (IL17B).

Mini Samples Mouse Interleukin 17B (IL17B) ELISA Kit

MEB700Mu-1x96wellstestplate 1x96-wells test plate
EUR 732.17
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mini Samples Mouse Interleukin 17B (IL17B).

Mini Samples Mouse Interleukin 17B (IL17B) ELISA Kit

MEB700Mu-5x96wellstestplate 5x96-wells test plate
EUR 2994.77
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mini Samples Mouse Interleukin 17B (IL17B).

Mini Samples Mouse Interleukin 17B (IL17B) ELISA Kit

4-MEB700Mu
  • EUR 5574.00
  • EUR 2945.00
  • EUR 733.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mini Samples Mouse Interleukin 17B (IL17B) in samples from n/a with no significant corss-reactivity with analogues from other species.

IL17B Human, Interleukin-17B Human Recombinant Protein, Sf9

PROTQ9UHF5-2 Regular: 5ug
EUR 317
Description: IL17B Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 169 amino acids (21-180a.a.) and having a molecular mass of 19.2kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). IL17B is expressed with a 6 amino acid His-tag at C-Terminus and purified by proprietary chromatographic techniques.

IL17B Human, Interleukin-17B Human Recombinant Protein, His Tag

PROTQ9UHF5 Regular: 25ug
EUR 317
Description: IL17B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 185 amino acids (21-180) and having a molecular mass of 20kDa.;IL17B is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Interleukin 17B,IL-17B ELISA Kit

201-12-2166 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

IL-17B Interleukin 17B Human Recombinant Protein

PROTQ9UHF5-1 Regular: 25ug
EUR 317
Description: Interleukin-17B Human Recombinant produced in E.Coli is a homodimeric, non-disulfide-linked polypeptide chain containing a total of 322 amino acids (2 chains of 161aa) and having a molecular mass of 36.5kDa. The IL-17B is purified by proprietary chromatographic techniques.

Human Interleukin 17B(IL-17B)ELISA Kit

QY-E04321 96T
EUR 361

Rat Interleukin 17B(IL-17B)ELISA Kit

QY-E10619 96T
EUR 361

Mouse Interleukin 17B(IL-17B)ELISA Kit

QY-E20839 96T
EUR 361

Recombinant Human Interleukin-17B/IL-17B (C-Fc)

CB78-10ug 10ug
EUR 141
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-17B/IL-17B (C-Fc)

CB78-1mg 1mg
EUR 1877
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-17B/IL-17B (C-Fc)

CB78-500ug 500ug
EUR 1328
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-17B/IL-17B (C-Fc)

CB78-50ug 50ug
EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human IL17B/ IL-17B Protein, Untagged, E.coli-100ug

QP10305-ec-100ug 100ug
EUR 988

Recombinant Human IL17B/ IL-17B Protein, Untagged, E.coli-250ug

QP10305-ec-250ug 250ug
EUR 1731

Recombinant Human IL17B/ IL-17B Protein, Untagged, E.coli-25ug

QP10305-ec-25ug 25ug
EUR 290

Recombinant Human IL17B/ IL-17B Protein, Untagged, E.coli-5ug

QP10305-ec-5ug 5ug
EUR 154

ELISA kit for Human Interleukin-17B

EK4287 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Interleukin-17B in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Mouse Interleukin-17B

EK4288 96 tests
EUR 469
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Interleukin-17B in samples from serum, plasma, tissue homogenates and other biological fluids.

Active Interleukin 33 (IL33)

4-APB980Hu01
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • EUR 1080.00
  • EUR 2060.00
  • EUR 655.00
  • EUR 7450.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 33 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 34 (IL34)

4-APC007Hu01
  • EUR 664.48
  • EUR 281.00
  • EUR 2216.80
  • EUR 805.60
  • EUR 1511.20
  • EUR 508.00
  • EUR 5392.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Active Interleukin 34 (IL34) expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 35 (IL35)

4-APC008Hu01
  • EUR 548.00
  • EUR 250.00
  • EUR 1780.00
  • EUR 660.00
  • EUR 1220.00
  • EUR 430.00
  • EUR 4300.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 35 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 28B (IL28B)

4-APC028Hu01
  • EUR 816.80
  • EUR 322.00
  • EUR 2788.00
  • EUR 996.00
  • EUR 1892.00
  • EUR 610.00
  • EUR 6820.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 28B expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 29 (IL29)

4-APC029Hu01
  • EUR 841.89
  • EUR 328.00
  • EUR 2882.08
  • EUR 1027.36
  • EUR 1954.72
  • EUR 626.00
  • EUR 7055.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 29 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 22 (IL22)

4-APC032Hu01
  • EUR 825.76
  • EUR 324.00
  • EUR 2821.60
  • EUR 1007.20
  • EUR 1914.40
  • EUR 616.00
  • EUR 6904.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 22 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 20 (IL20)

4-APC058Hu01
  • EUR 592.80
  • EUR 262.00
  • EUR 1948.00
  • EUR 716.00
  • EUR 1332.00
  • EUR 460.00
  • EUR 4720.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 20 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 24 (IL24)

4-APC064Hu01
  • EUR 592.80
  • EUR 262.00
  • EUR 1948.00
  • EUR 716.00
  • EUR 1332.00
  • EUR 460.00
  • EUR 4720.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 24 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 17D (IL17D)

4-APD346Hu01
  • EUR 637.60
  • EUR 274.00
  • EUR 2116.00
  • EUR 772.00
  • EUR 1444.00
  • EUR 490.00
  • EUR 5140.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 17D expressed in: E.coli

Active Interleukin 17C (IL17C)

4-APD347Hu01
  • EUR 637.60
  • EUR 274.00
  • EUR 2116.00
  • EUR 772.00
  • EUR 1444.00
  • EUR 490.00
  • EUR 5140.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 17C expressed in: E.coli

Active Interleukin 10 (IL10)

4-APA056Hu61
  • EUR 849.95
  • EUR 331.00
  • EUR 2912.32
  • EUR 1037.44
  • EUR 1974.88
  • EUR 632.00
  • EUR 7130.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 10 expressed in: 293F cell

We showed that Human p.R281Q gp130 associated with selective loss IL – 11 signals without affecting the IL – 6 IL -27, OSM, LIF, CT1, CLC, and CNTF signal. In mice Il6st p.R279Q reduce the size of garbage and cause synostosis facial and dental abnormalities. Effects on IL – 11 signaling induced by gp130 variants showed incomplete penetrance but phenocopies aspect IL 11 RA deficiencies in the human and mice. Our data indicate that genetically in pleiotropic cytokine receptor variants may have a very selective flaw.

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Antibodies, Assay Kits, Biology Cells, cDNA, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, DNA Testing, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, NATtrol, Panel, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Uncategorized, Vector & Virus, Western Blot

Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.

Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.

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