Introduction CRISPR / system CAS9, which can be utilized in vitro biological experiments have recently caught a lot of attention for their important role and benefits. However, realization of the full potential of CRISPR / CAS9 approach requires addressing the various challenges and side effects. Expression gene and the potential side effects of the CRISPR / CAS9 in Human cells that are still to be explained.

The aim of our study was to explore the effect of CRISPR / CAS9 on gene expression in 293T cells. A Cas9-expressing plasmid PX458 and PX458 Cas9-T2A-off plasmids used to study the role of CRISPR / CAS9 at set gene expression in 293T cells. Gene expression in 293T cells after transfection of plasmid PX458 or PX458-T2A plasmid RNA was detected by sequencing and correlative statistical analysis. Differential gene expression in transfected 293T second PX458 and PX458-T2A cells transfected 293T 293T cells compared with normal cells detected using chain quantitative reverse transcription polymerase reaction (RT qPCR). MRNA and protein levels were measured using reverse transcription PCR and Western blot.

Co-IP assay combined with a shotgun LC-MS / MS is used to investigate differences NGFR protein-interaction between PX458 and PX458 transfected 293T cells transfected 293T cell-T2A. In this study, we observed that the PX458 plasmid transfection and expression Cas9 can affect the expression of different gene , including FOSB (FBJ murine osteosarcoma virus Onco gene homolog B), IL – 11 (Interleukin- 11 ), MMP1 (matrix metalloproteinases), CYP2D6 (CytochromeP4502D6), and NGFR (matrix metalloproteinase 1).

Downregulation of NGFR after transfection PX458 confirmed by RT qPCR and western blot analysis. NGFR expression was significantly lowered in PX458 transfected 293T 293T cells than in normal cells and PX458-T2A transfected 293T cells. Dilution co-IP was analyzed with a shotgun LC-MS / MS showed total 183 proteins interact with NGFR in 293T cells transfected PX458 while 221 proteins interact with NGFR-T2A PX458 identified in transfected 293T cells using machine mascot.

Cas9 expression by transfection of plasmid PX458 negatively correlated with the level NGFR NGFR mRNA and protein expression in 293T cells, while the PX458-T2A, where Cas9 disabled, does not affect the expression of NGFR. Decreased expression of NGFR also affects the number of proteins that interact with NGFR. These results indicate that the effect Cas9 in NGFR expression and other expressions gene should be considered when developing cell-based research and therapy utilizing the CRISPR / CAS9 system.

Profile inflammation and osteogenic hematoma Fracture Human Potential. form of fracture hematoma immediately after the fracture and is considered important for bone healing process. molecular composition has been briefly investigated the existence of our current understanding is based on animal studies.

Active Interleukin 13 (IL13)
RPU56351-100ug	Biomatik Corporation	100ug	EUR 985.6

Active Interleukin 13 (IL13)
RPU56351-1mg	Biomatik Corporation	1mg	EUR 4941.3

Active Interleukin 13 (IL13)
RPU56351-50ug	Biomatik Corporation	50ug	EUR 760.4

Human Interleukin 13 (IL13) Protein (Active)
20-abx655715	Abbexa	EUR 1328.40 EUR 477.60 EUR 4436.40 EUR 1612.80 EUR 910.80	100 ug 10 ug 1 mg 200 ug 50 ug

Active Interleukin 10 (IL10)
4-APA056Hu61	Cloud-Clone	EUR 1019.94 EUR 397.20 EUR 3494.78 EUR 1244.93 EUR 2369.86 EUR 758.40 EUR 8556.96	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 10 expressed in: 293F cell

Active Interleukin 11 (IL11)
4-APA057Hu01	Cloud-Clone	EUR 1087.68 EUR 415.20 EUR 3748.80 EUR 1329.60 EUR 2539.20 EUR 804.00 EUR 9192.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 11 expressed in: E.coli

Active Interleukin 15 (IL15)
4-APA061Hu01	Cloud-Clone	EUR 1195.20 EUR 444.00 EUR 4152.00 EUR 1464.00 EUR 2808.00 EUR 876.00 EUR 10200.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 15 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 16 (IL16)
4-APA062Hu01	Cloud-Clone	EUR 1087.68 EUR 415.20 EUR 3748.80 EUR 1329.60 EUR 2539.20 EUR 804.00 EUR 9192.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 16 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 17 (IL17)
4-APA063Hu01	Cloud-Clone	EUR 603.84 EUR 285.60 EUR 1934.40 EUR 724.80 EUR 1329.60 EUR 480.00 EUR 4656.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 17 expressed in: E.coli

Active Interleukin 18 (IL18)
4-APA064Hu01	Cloud-Clone	EUR 797.38 EUR 337.20 EUR 2660.16 EUR 966.72 EUR 1813.44 EUR 609.60 EUR 6470.40	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 18 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 18 (IL18)
4-APA064Mu01	Cloud-Clone	EUR 689.86 EUR 308.40 EUR 2256.96 EUR 832.32 EUR 1544.64 EUR 537.60 EUR 5462.40	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Interleukin 18 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 21 (IL21)
4-APB688Hu01	Cloud-Clone	EUR 790.92 EUR 334.80 EUR 2635.97 EUR 958.66 EUR 1797.31 EUR 604.80 EUR 6409.92	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 21 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 25 (IL25)
4-APB694Hu01	Cloud-Clone	EUR 765.12 EUR 328.80 EUR 2539.20 EUR 926.40 EUR 1732.80 EUR 588.00 EUR 6168.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 25 expressed in: E.coli

Active Interleukin 33 (IL33)
4-APB980Hu01	Cloud-Clone	EUR 1060.80 EUR 408.00 EUR 3648.00 EUR 1296.00 EUR 2472.00 EUR 786.00 EUR 8940.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 33 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 34 (IL34)
4-APC007Hu01	Cloud-Clone	EUR 797.38 EUR 337.20 EUR 2660.16 EUR 966.72 EUR 1813.44 EUR 609.60 EUR 6470.40	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Active Interleukin 34 (IL34) expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 35 (IL35)
4-APC008Hu01	Cloud-Clone	EUR 657.60 EUR 300.00 EUR 2136.00 EUR 792.00 EUR 1464.00 EUR 516.00 EUR 5160.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 35 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 29 (IL29)
4-APC029Hu01	Cloud-Clone	EUR 1010.27 EUR 393.60 EUR 3458.50 EUR 1232.83 EUR 2345.66 EUR 751.20 EUR 8466.24	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 29 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 22 (IL22)
4-APC032Hu01	Cloud-Clone	EUR 990.91 EUR 388.80 EUR 3385.92 EUR 1208.64 EUR 2297.28 EUR 739.20 EUR 8284.80	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 22 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 20 (IL20)
4-APC058Hu01	Cloud-Clone	EUR 711.36 EUR 314.40 EUR 2337.60 EUR 859.20 EUR 1598.40 EUR 552.00 EUR 5664.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 20 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 24 (IL24)
4-APC064Hu01	Cloud-Clone	EUR 711.36 EUR 314.40 EUR 2337.60 EUR 859.20 EUR 1598.40 EUR 552.00 EUR 5664.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 24 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 10 (IL10)
RPU54838-100ug	Biomatik Corporation	100ug	EUR 1030.7

Active Interleukin 10 (IL10)
RPU54838-1mg	Biomatik Corporation	1mg	EUR 4569.5

Active Interleukin 10 (IL10)
RPU54838-50ug	Biomatik Corporation	50ug	EUR 828.3

Active Interleukin 11 (IL11)
RPU54855-100ug	Biomatik Corporation	100ug	EUR 1108.8

Active Interleukin 11 (IL11)
RPU54855-1mg	Biomatik Corporation	1mg	EUR 4914

Active Interleukin 11 (IL11)
RPU54855-50ug	Biomatik Corporation	50ug	EUR 891

Active Interleukin 15 (IL15)
RPU54856-100ug	Biomatik Corporation	100ug	EUR 1232

Active Interleukin 15 (IL15)
RPU54856-1mg	Biomatik Corporation	1mg	EUR 6240

Active Interleukin 15 (IL15)
RPU54856-50ug	Biomatik Corporation	50ug	EUR 990

Active Interleukin 16 (IL16)
RPU54857-100ug	Biomatik Corporation	100ug	EUR 1108.8

Active Interleukin 16 (IL16)
RPU54857-1mg	Biomatik Corporation	1mg	EUR 4914

Active Interleukin 16 (IL16)
RPU54857-50ug	Biomatik Corporation	50ug	EUR 891

Active Interleukin 17 (IL17)
RPU54858-100ug	Biomatik Corporation	100ug	EUR 514.8

Active Interleukin 17 (IL17)
RPU54858-1mg	Biomatik Corporation	1mg	EUR 2607.8

Active Interleukin 17 (IL17)
RPU54858-50ug	Biomatik Corporation	50ug	EUR 401.3

Active Interleukin 18 (IL18)
RPU54859-100ug	Biomatik Corporation	100ug	EUR 722.7

Active Interleukin 18 (IL18)
RPU54859-1mg	Biomatik Corporation	1mg	EUR 3199.3

Active Interleukin 18 (IL18)
RPU54859-50ug	Biomatik Corporation	50ug	EUR 579.7

Active Interleukin 25 (IL25)
RPU54937-100ug	Biomatik Corporation	100ug	EUR 739.2

Active Interleukin 25 (IL25)
RPU54937-1mg	Biomatik Corporation	1mg	EUR 3276

Active Interleukin 25 (IL25)
RPU54937-50ug	Biomatik Corporation	50ug	EUR 594

Active Interleukin 35 (IL35)
RPU54947-100ug	Biomatik Corporation	100ug	EUR 616

Active Interleukin 35 (IL35)
RPU54947-1mg	Biomatik Corporation	1mg	EUR 2730

Active Interleukin 35 (IL35)
RPU54947-50ug	Biomatik Corporation	50ug	EUR 495

Active Interleukin 20 (IL20)
RPU54948-100ug	Biomatik Corporation	100ug	EUR 675.4

Active Interleukin 20 (IL20)
RPU54948-1mg	Biomatik Corporation	1mg	EUR 3419

Active Interleukin 20 (IL20)
RPU54948-50ug	Biomatik Corporation	50ug	EUR 526.1

Active Interleukin 24 (IL24)
RPU54949-100ug	Biomatik Corporation	100ug	EUR 651.2

Active Interleukin 24 (IL24)
RPU54949-1mg	Biomatik Corporation	1mg	EUR 3294.2

Active Interleukin 24 (IL24)
RPU54949-50ug	Biomatik Corporation	50ug	EUR 506.9

Active Interleukin 18 (IL18)
RPU55467-100ug	Biomatik Corporation	100ug	EUR 739.2

Active Interleukin 18 (IL18)
RPU55467-1mg	Biomatik Corporation	1mg	EUR 3731

Active Interleukin 18 (IL18)
RPU55467-50ug	Biomatik Corporation	50ug	EUR 574.1

Active Interleukin 21 (IL21)
RPU55704-100ug	Biomatik Corporation	100ug	EUR 997.7

Active Interleukin 21 (IL21)
RPU55704-1mg	Biomatik Corporation	1mg	EUR 3893.5

Active Interleukin 21 (IL21)
RPU55704-50ug	Biomatik Corporation	50ug	EUR 599.1

Active Interleukin 33 (IL33)
RPU55739-100ug	Biomatik Corporation	100ug	EUR 1013.1

Active Interleukin 33 (IL33)
RPU55739-1mg	Biomatik Corporation	1mg	EUR 5116.8

Active Interleukin 33 (IL33)
RPU55739-50ug	Biomatik Corporation	50ug	EUR 787.2

Active Interleukin 34 (IL34)
RPU55743-100ug	Biomatik Corporation	100ug	EUR 997.7

Active Interleukin 34 (IL34)
RPU55743-1mg	Biomatik Corporation	1mg	EUR 3931.2

Active Interleukin 34 (IL34)
RPU55743-50ug	Biomatik Corporation	50ug	EUR 604.8

Active Interleukin 29 (IL29)
RPU55746-100ug	Biomatik Corporation	100ug	EUR 651.2

Active Interleukin 29 (IL29)
RPU55746-1mg	Biomatik Corporation	1mg	EUR 3294.2

Active Interleukin 29 (IL29)
RPU55746-50ug	Biomatik Corporation	50ug	EUR 506.9

Active Interleukin 22 (IL22)
RPU55748-100ug	Biomatik Corporation	100ug	EUR 1282.6

Active Interleukin 22 (IL22)
RPU55748-1mg	Biomatik Corporation	1mg	EUR 5054.4

Active Interleukin 22 (IL22)
RPU55748-50ug	Biomatik Corporation	50ug	EUR 777.6

Active Interleukin 32 (IL32)
RPU58896-100ug	Biomatik Corporation	100ug	EUR 709.8

Active Interleukin 32 (IL32)
RPU58896-1mg	Biomatik Corporation	1mg	EUR 3294.7

Active Interleukin 32 (IL32)
RPU58896-50ug	Biomatik Corporation	50ug	EUR 522.7

Active Interleukin 19 (IL19)
RPU58930-100ug	Biomatik Corporation	100ug	EUR 868.2

Active Interleukin 19 (IL19)
RPU58930-1mg	Biomatik Corporation	1mg	EUR 3419.5

Active Interleukin 19 (IL19)
RPU58930-50ug	Biomatik Corporation	50ug	EUR 542.5

Active Interleukin 10 (IL10)
RPU59057-100ug	Biomatik Corporation	100ug	EUR 939.7

Active Interleukin 10 (IL10)
RPU59057-1mg	Biomatik Corporation	1mg	EUR 3673.8

Active Interleukin 10 (IL10)
RPU59057-50ug	Biomatik Corporation	50ug	EUR 587.2

Active Interleukin 31 (IL31)
RPU59177-100ug	Biomatik Corporation	100ug	EUR 1084.2

Active Interleukin 31 (IL31)
RPU59177-1mg	Biomatik Corporation	1mg	EUR 4504.5

Active Interleukin 31 (IL31)
RPU59177-50ug	Biomatik Corporation	50ug	EUR 720

Active Interleukin 22 (IL22)
RPU59213-100ug	Biomatik Corporation	100ug	EUR 1069.2

Active Interleukin 22 (IL22)
RPU59213-1mg	Biomatik Corporation	1mg	EUR 4738.5

Active Interleukin 22 (IL22)
RPU59213-50ug	Biomatik Corporation	50ug	EUR 712.8

Active Interleukin 10 (IL10)
RPU59216-100ug	Biomatik Corporation	100ug	EUR 1082.4

Active Interleukin 10 (IL10)
RPU59216-1mg	Biomatik Corporation	1mg	EUR 4797

Active Interleukin 10 (IL10)
RPU59216-50ug	Biomatik Corporation	50ug	EUR 721.6

Active Interleukin 11 (IL11)
RPU59219-100ug	Biomatik Corporation	100ug	EUR 1084.1

Active Interleukin 11 (IL11)
RPU59219-1mg	Biomatik Corporation	1mg	EUR 4802.9

Active Interleukin 11 (IL11)
RPU59219-50ug	Biomatik Corporation	50ug	EUR 722.5

Active Interleukin 26 (IL26)
RPU59230-100ug	Biomatik Corporation	100ug	EUR 1093.1

Active Interleukin 26 (IL26)
RPU59230-1mg	Biomatik Corporation	1mg	EUR 4843.8

Active Interleukin 26 (IL26)
RPU59230-50ug	Biomatik Corporation	50ug	EUR 728.6

Active Interleukin 10 (IL10)
RPU56353-100ug	Biomatik Corporation	100ug	EUR 1282.6

Active Interleukin 10 (IL10)
RPU56353-1mg	Biomatik Corporation	1mg	EUR 5054.4

Active Interleukin 10 (IL10)
RPU56353-50ug	Biomatik Corporation	50ug	EUR 777.6

Active Interleukin 10 (IL10)
RPU56368-100ug	Biomatik Corporation	100ug	EUR 1078

Active Interleukin 10 (IL10)
RPU56368-1mg	Biomatik Corporation	1mg	EUR 4777.5

Active Interleukin 10 (IL10)
RPU56368-50ug	Biomatik Corporation	50ug	EUR 866.8

Active Interleukin 2 (IL2)
4-APA073Hu61	Cloud-Clone	EUR 872.64 EUR 357.60 EUR 2942.40 EUR 1060.80 EUR 2001.60 EUR 660.00 EUR 7176.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 2 expressed in: 293F cell

Active Interleukin 2 (IL2)
4-APA073Mu61	Cloud-Clone	EUR 808.13 EUR 339.60 EUR 2700.48 EUR 980.16 EUR 1840.32 EUR 616.80 EUR 6571.20	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Interleukin 2 expressed in: 293F cell

Active Interleukin 4 (IL4)
4-APA077Hu01	Cloud-Clone	EUR 798.46 EUR 337.20 EUR 2664.19 EUR 968.06 EUR 1816.13 EUR 609.60 EUR 6480.48	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 4 expressed in: E.coli

Active Interleukin 4 (IL4)
4-APA077Hu61	Cloud-Clone	EUR 939.30 EUR 375.60 EUR 3192.38 EUR 1144.13 EUR 2168.26 EUR 704.40 EUR 7800.96	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 4 expressed in: 293F cell

Active Interleukin 4 (IL4)
4-APA077Mu01	Cloud-Clone	EUR 781.25 EUR 332.40 EUR 2599.68 EUR 946.56 EUR 1773.12 EUR 598.80 EUR 6319.20	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Interleukin 4 expressed in: E.coli

Active Interleukin 4 (IL4)
4-APA077Ra01	Cloud-Clone	EUR 995.21 EUR 390.00 EUR 3402.05 EUR 1214.02 EUR 2308.03 EUR 741.60 EUR 8325.12	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Interleukin 4 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 6 (IL6)
4-APA079Hu01	Cloud-Clone	EUR 872.64 EUR 357.60 EUR 2942.40 EUR 1060.80 EUR 2001.60 EUR 660.00 EUR 7176.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 6 expressed in: E.coli

Active Interleukin 6 (IL6)
4-APA079Hu61	Cloud-Clone	EUR 968.33 EUR 382.80 EUR 3301.25 EUR 1180.42 EUR 2240.83 EUR 723.60 EUR 8073.12	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 6 expressed in: 293F cell

Active Interleukin 6 (IL6)
4-APA079Mu61	Cloud-Clone	EUR 942.53 EUR 375.60 EUR 3204.48 EUR 1148.16 EUR 2176.32 EUR 706.80 EUR 7831.20	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Interleukin 6 expressed in: 293F cell

Active Interleukin 6 (IL6)
4-APA079Ra61	Cloud-Clone	EUR 872.64 EUR 357.60 EUR 2942.40 EUR 1060.80 EUR 2001.60 EUR 660.00 EUR 7176.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Interleukin 6 expressed in: 293F cell

Active Interleukin 8 (IL8)
4-APA080Hu01	Cloud-Clone	EUR 700.61 EUR 310.80 EUR 2297.28 EUR 845.76 EUR 1571.52 EUR 544.80 EUR 5563.20	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 8 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 7 (IL7)
4-APA662Hu01	Cloud-Clone	EUR 993.06 EUR 390.00 EUR 3393.98 EUR 1211.33 EUR 2302.66 EUR 740.40 EUR 8304.96	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Interleukin 7 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Interleukin 4 (IL4)
RPU54749-100ug	Biomatik Corporation	100ug	EUR 777.7

Active Interleukin 4 (IL4)
RPU54749-1mg	Biomatik Corporation	1mg	EUR 3445

Active Interleukin 4 (IL4)
RPU54749-50ug	Biomatik Corporation	50ug	EUR 624.8

Active Interleukin 2 (IL2)
RPU54751-100ug	Biomatik Corporation	100ug	EUR 453.2

Active Interleukin 2 (IL2)
RPU54751-1mg	Biomatik Corporation	1mg	EUR 2009.8

Active Interleukin 2 (IL2)
RPU54751-50ug	Biomatik Corporation	50ug	EUR 364.1

Active Interleukin 4 (IL4)
RPU54828-100ug	Biomatik Corporation	100ug	EUR 822.8

Active Interleukin 4 (IL4)
RPU54828-1mg	Biomatik Corporation	1mg	EUR 3244.8

Active Interleukin 4 (IL4)
RPU54828-50ug	Biomatik Corporation	50ug	EUR 499.2

Active Interleukin 6 (IL6)
RPU54829-100ug	Biomatik Corporation	100ug	EUR 1045

Active Interleukin 6 (IL6)
RPU54829-1mg	Biomatik Corporation	1mg	EUR 5253.3

Active Interleukin 6 (IL6)
RPU54829-50ug	Biomatik Corporation	50ug	EUR 808.4

Active Interleukin 6 (IL6)
RPU54832-100ug	Biomatik Corporation	100ug	EUR 971.3

The purpose of this study to analyze the content of inflammatory cytokines in the fracture hematoma Human and determine their effect on osteoprogenitor cells. Twenty-three patients were recruited following informed consent. peripheral blood, and bone fracture hematoma collected. A Luminex assay at the level of 34 cytokines done and autologous peripheral blood samples served as controls. Mesenchymal Stem Cells (MSCs) were isolated following collagenase digestion and functional tests performed. Gene expression analysis of 84 key osteogenic molecules do.